As you can imagine, cigarette smoke contains many impurities that are inhaled in great numbers directly into the lung. For this reason, the alveolar spaces of the smoker contain numerous scavenger cells (macrophages) that are filled with engulfed (phagocytized) particles of impurities and debris, as illustrated in Picture of scavenger cells in a smoker's alveolus Under the microscope, with this high magnification, you can actually see the black and brown engulfed particles in the alveolar scavenger cells. Indeed, smoker's lung may have so much of this particulate material that the lung looks gray-black to the naked eye. Most of the time, you don't need a microscope to tell if someone is or was a heavy smoker. A naked eye examination of a smoker's lung will usually reveal an enlarged gray-black lung with enlarged air spaces (the emphysema, as you saw in Figure 4 and will see again in Figure 8).